METHOD FOR PRODUCING PURINE NUCLEOSIDES AND NUCLEOTIDES BY FERMENTATION USING A BACTERIUM BELONGING TO THE GENUS ESCHERICHIA OR BACILLUS

A method is provided for producing a purine nucleoside, such as inosine and guanosine, and a method for producing a 5'-purine nucleotide such as 5'-inosinic acid or 5'-guanylic acid, using a bacterium belonging to the either genus Escherichia or genus Bacillus, wherein purine nucleosi...

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Hauptverfasser: LIVSHITS VITALY ARKADIEVICH, KUTUKOVA EKATERINA ALEKSANDROVNA, ZAKATAEVA NATALIA PAVLOVNA
Format: Patent
Sprache:eng
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Zusammenfassung:A method is provided for producing a purine nucleoside, such as inosine and guanosine, and a method for producing a 5'-purine nucleotide such as 5'-inosinic acid or 5'-guanylic acid, using a bacterium belonging to the either genus Escherichia or genus Bacillus, wherein purine nucleoside productivity of said bacterium is enhanced by enhancing an activity of a protein encoded by the yeaS (leuE) gene.