Microencapsulation and sustained release of biologically active polypeptides

Microencapsulation and sustained release of biologically active polypeptides

The invention relates to compositions and methods for the sustained release of biologically active polypeptides. The sustained release compositions of this invention comprise a biocompatible polymer having dispersed therein a biologically active polypeptide, and a corticosteroid to modify the releas...

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Hauptverfasser: STEITZ-ABADI SUSAN A, RILEY M. GARY I, HOTZ JOYCE M, BURKE PAUL A, DASCH JAMES R, COSTANTINO HENRY R, ZALE STEPHEN E
Format: Patent
Sprache:eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator STEITZ-ABADI SUSAN A
RILEY M. GARY I
HOTZ JOYCE M
BURKE PAUL A
DASCH JAMES R
COSTANTINO HENRY R
ZALE STEPHEN E
description The invention relates to compositions and methods for the sustained release of biologically active polypeptides. The sustained release compositions of this invention comprise a biocompatible polymer having dispersed therein a biologically active polypeptide, and a corticosteroid to modify the release profile and provide increased bioavailability.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title Microencapsulation and sustained release of biologically active polypeptides
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