Microencapsulation and sustained release of biologically active polypeptides

The invention relates to compositions and methods for the sustained release of biologically active polypeptides. The sustained release compositions of this invention comprise a biocompatible polymer having dispersed therein a biologically active polypeptide, and a corticosteroid to modify the releas...

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Bibliographische Detailangaben
Hauptverfasser:	STEITZ-ABADI SUSAN A, RILEY M. GARY I, HOTZ JOYCE M, BURKE PAUL A, DASCH JAMES R, COSTANTINO HENRY R, ZALE STEPHEN E
Format:	Patent
Sprache:	eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The invention relates to compositions and methods for the sustained release of biologically active polypeptides. The sustained release compositions of this invention comprise a biocompatible polymer having dispersed therein a biologically active polypeptide, and a corticosteroid to modify the release profile and provide increased bioavailability.