SYSTEMS AND METHODS FOR CREATING ENLARGED MIGRATION CHANNELS FOR THERAPEUTIC AGENTS WITHIN THE ENDOTHELIUM

A system for enlarging endothelium migration channels at a treatment site in a coronary vessel wall, to enable enhanced delivery of a therapeutic agent thereto. The system includes an enlarging agent, for enlarging endothelium migration channels at a treatment site in a coronary vessel wall. It also...

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Hauptverfasser: CHOW MINA, WEBLER, JR. WILLIAM E, BRIGHT RACHEL, YRIBARREN TRAVIS R, CHAN GREGORY W, NGUYEN BINH T, OEPEN RANDOLF VON, EHRENREICH KEVIN J
Format: Patent
Sprache:eng
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Zusammenfassung:A system for enlarging endothelium migration channels at a treatment site in a coronary vessel wall, to enable enhanced delivery of a therapeutic agent thereto. The system includes an enlarging agent, for enlarging endothelium migration channels at a treatment site in a coronary vessel wall. It also includes a delivery system, for delivering the enlarging agent to the treatment site, so that the enlarging agent will be delivered thereby to enlarge the endothelium migration channels at the treatment site, and for delivering the therapeutic agent to the delivery site. The therapeutic agent will thereby be delivered into the enlarged migration channels at the treatment site, to treat the treatment site with the therapeutic agent.