Polymorphic Form of Lercanidipine Hydrochloride and Process for the Preparation Thereof

Polymorphic Form of Lercanidipine Hydrochloride and Process for the Preparation Thereof

Processes for the purification of lercanidipine hydrochloride are provided which uses a binary system of an alcohol-containing solvent such as methanol and an aliphatic ester-containing solvent such as isopropyl acetate. Processes for the preparation of substantially amorphous lercanidipine hydrochl...

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Bibliographische Detailangaben
Hauptverfasser: SAWANT MANGESH SHIVRAM, KHAN MUBEEN AHMED, BISWAS MALOYESH MATHURESH, PRADHAN NITIN SHARAD CHANDRA, SINHA SUKUMAR
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Zusammenfassung:Processes for the purification of lercanidipine hydrochloride are provided which uses a binary system of an alcohol-containing solvent such as methanol and an aliphatic ester-containing solvent such as isopropyl acetate. Processes for the preparation of substantially amorphous lercanidipine hydrochloride are also provided. Also provided is lercanidipine hydrochloride substantially in polymorph form V.