PROCESS FOR PREPARING PARTICLES OF PROTEINACEOUS MATERIAL

Protein particles are prepared by causing or allowing protein molecules dispersed in a liquid medium at a concentration of 8 mg.mL-1 or greater to react in the presence of a zero-length crosslinker, so as to produce protein particles comprising protein molecules that are covalently bonded together....

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Bibliographische Detailangaben
Hauptverfasser: WOODROW JOHN RODNEY, JOHNSON RICHARD ALAN
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Protein particles are prepared by causing or allowing protein molecules dispersed in a liquid medium at a concentration of 8 mg.mL-1 or greater to react in the presence of a zero-length crosslinker, so as to produce protein particles comprising protein molecules that are covalently bonded together. The protein particles may be produced with sizes in the sub-micron range with closely defined sizes and size distributions. The particles have applications in many fields, but are useful inter alia for the delivery of therapeutic agents and other agents, eg imaging contrast agents, to the body.