Genetically Engineered and Phenotyped Mice and Stem Cell Clones for Producing the Same

The current invention relates to genetically engineered mice, cells derived from those mice, and polynucleotides and polypeptides corresponding to genes affected by the engineered mutation. The invention also relates to antibodies raised in a mouse of the invention. The invention further provides me...

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Bibliographische Detailangaben
Hauptverfasser: ZAMBROWICZ BRIAN, MONTGOMERY CHARLES, VOGEL PETER, SHI ZHENG-ZHENG, EDWARDS JOEL A, RANGEL CAROLINA, SPARKS MARY JEAN, ABUIN ALEJANDRO, SANDS ARTHUR T
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The current invention relates to genetically engineered mice, cells derived from those mice, and polynucleotides and polypeptides corresponding to genes affected by the engineered mutation. The invention also relates to antibodies raised in a mouse of the invention. The invention further provides methods for using the mice, cells, polynucleotides, polypeptides and antibodies of the invention.