Gene Signature of Early Hypoxia to Predict Patient Survival

The present invention provides methods and compositions for predicting patient responses to cancer treatment using hypoxia gene signatures. These methods can comprise measuring in a biological sample from a patient the levels of gene expression of a group of the genes designated herein. The present...

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Hauptverfasser: SEIGNEURIC RENAUD G, NUYTEN DIMITRY S.A, FUNG GLENN, VAN ERK ARIE, KRISHNAN SRIRAM, RAO R. BHARAT, WOUTERS BRADLY G, STARMANS MAUD H.W, KRISHNAPURAM BALAJI, ROUSCHOP KASPER M, BEGG ADRIAN CAMPBELL, EVELO CHRISTOFFEL THEODORUS ANTHONIUS, MAGAGNIN MICHAEL GASTON, LAMBIN PHILIPPE
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention provides methods and compositions for predicting patient responses to cancer treatment using hypoxia gene signatures. These methods can comprise measuring in a biological sample from a patient the levels of gene expression of a group of the genes designated herein. The present invention also provides for microarrays that can detect expression from a group of genes.