Genetically Engineered and Phenotyped Mice and Stem Cell Clones for Producing the Same

The current invention relates to genetically engineered mice, cells derived from those mice, and polynucleotides and polypeptides corresponding to genes affected by the engineered mutation. The invention also relates to antibodies raised in a mouse of the invention. The invention further provides me...

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Hauptverfasser: STALA JOY ANNE, GREEN LESLIE JANE, MONTGOMERY CHARLES, BORROMEO MARK DOMINIC, VOGEL PETER, MASSEY ERIN MARIE, MCLAIN DINA REBECCA, DING ZHI-YONG, CULBERTSON LING LING, HORNER ALLISON ANNE BYERS, SANDS ARTHUR T, FAN LIANGFEN, COMBS KATHERIN E, ZAMBROWICZ BRIAN, EDWARDS JOEL, SHI ZHENG-ZHENG, GIRGIS ROSEMARY, MINZE LAURIE JEANETTE, RANGEL CAROLINA, SPARKS MARY JEAN, ABUIN ALEJANDRO, SEVAUX TRACY ELLEN WILLIS, PAYNE BOBBY JOE
Format: Patent
Sprache:eng
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Zusammenfassung:The current invention relates to genetically engineered mice, cells derived from those mice, and polynucleotides and polypeptides corresponding to genes affected by the engineered mutation. The invention also relates to antibodies raised in a mouse of the invention. The invention further provides methods for using the mice, cells, polynucleotides, polypeptides and antibodies of the invention.