Tamper resistant lipid-based oral dosage form for opioid agonists

A tamper resistant drug delivery system made of at least one lipid, at least one gelling agent and at least one drug active, such as oxycodone, where the system gels rapidly in the presence of water or a solution containing water, and the drug active releases into the digestive system, wherein the w...

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Hauptverfasser: BAUSCH JAMES M, LEWIS LINDA L, SHEAR JEFF L, KERSHMAN ALVIN
Format: Patent
Sprache:eng
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Zusammenfassung:A tamper resistant drug delivery system made of at least one lipid, at least one gelling agent and at least one drug active, such as oxycodone, where the system gels rapidly in the presence of water or a solution containing water, and the drug active releases into the digestive system, wherein the weight ratio of gelling agent to lipid is less than 1:1.4.