Process for Producing Simvastatin

The present invention discloses a process for producing Simvastatin and intermediate thereof. The present invention uses inexpensive and easily available reagents, its condition is mild, and it leaves out the protective and deprotective steps, which are necessary in prior methods. Compared with prio...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: SUN MEG M, ZHU ZUOLIN, YE HONGPING
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention discloses a process for producing Simvastatin and intermediate thereof. The present invention uses inexpensive and easily available reagents, its condition is mild, and it leaves out the protective and deprotective steps, which are necessary in prior methods. Compared with prior art, the esterifying condition in 8-position is greatly simplified.