SILDENAFIL N-OXIDE AS PRODRUG

Embodiments of the present invention relate to a compound of formula (1A) or a pharmacologically acceptable salt, hydrate, or solvate thereof. Other embodiments of the present invention relate to a pharmaceutical composition containing this compound, to methods for preparing this compound, and to me...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: TURSKI LECHOSLAW A, KRUSE CORNELIS G, STOIT AXEL, VADER SANDER, TULP MARTINUS TH.M
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Embodiments of the present invention relate to a compound of formula (1A) or a pharmacologically acceptable salt, hydrate, or solvate thereof. Other embodiments of the present invention relate to a pharmaceutical composition containing this compound, to methods for preparing this compound, and to methods for preparing compositions containing this compound. Yet other embodiments of the invention relate to uses of this compound, and compositions containing it, for the manufacture of medicaments and pharmaceutical compositions for treating erectile dysfunction or pulmonary arterial hypertension.