AAV vectors for gene delivery to the lung

Methods of making and using recombinant AAV vectors and virions for gene delivery to the lung are described. The recombinant AAV virions are derived from caprine AAV and bovine AAV, both of which display tropism for lung tissue.

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Bibliographische Detailangaben
Hauptverfasser: ARBETMAN ALEJANDRA E, LOCHRIE MICHAEL A
Format: Patent
Sprache:eng
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Zusammenfassung:Methods of making and using recombinant AAV vectors and virions for gene delivery to the lung are described. The recombinant AAV virions are derived from caprine AAV and bovine AAV, both of which display tropism for lung tissue.