Methods for preparing eszopiclone

Methods for the preparation of crystalline eszopiclone free base in water, in the absence of organic solvents, are provided. The methods are more environmentally acceptable than prior art methods, and produce eszopiclone free base essentially free of residual organic solvent.

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Bibliographische Detailangaben
Hauptverfasser: MENDELOVICI MARIOARA, RAMATY REVITAL, FINKELSTEIN NINA, MAINFELD ALEX
Format: Patent
Sprache:eng
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Zusammenfassung:Methods for the preparation of crystalline eszopiclone free base in water, in the absence of organic solvents, are provided. The methods are more environmentally acceptable than prior art methods, and produce eszopiclone free base essentially free of residual organic solvent.