Crystalline Forms of 3-[5-Chloro-4-[(2,4-Difluorobenzyl) Oxy]-6-Oxopyrimidin-1(6H)-Yl]-N-(2-Hydroxyethyl)-4-Methylbenzamide

Crystalline Forms of 3-[5-Chloro-4-[(2,4-Difluorobenzyl) Oxy]-6-Oxopyrimidin-1(6H)-Yl]-N-(2-Hydroxyethyl)-4-Methylbenzamide

Crystalline forms of the p38 kinase inhibitor 3-[5-chloro-4-[(2,4-difluorobenzyl)oxy]-6-oxopyrimidin-1(6H)-yl]-N-(2-hydroxyethyl)-4-methylbenzamide is provided. Also provided are combinations and pharmaceutical compositions comprising the crystalline forms, and methods for the prophylaxis and/or tre...

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Bibliographische Detailangaben
1. Verfasser: SELBO JON G
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Zusammenfassung:Crystalline forms of the p38 kinase inhibitor 3-[5-chloro-4-[(2,4-difluorobenzyl)oxy]-6-oxopyrimidin-1(6H)-yl]-N-(2-hydroxyethyl)-4-methylbenzamide is provided. Also provided are combinations and pharmaceutical compositions comprising the crystalline forms, and methods for the prophylaxis and/or treatment of a p38 kinase-mediated condition comprising administering to a subject a therapeutically effective amount of the crystalline forms.