Indole Derivatives and Use Thereof as Kinase Inhibitors in Particular Ikk2 Inhibitors

Indole Derivatives and Use Thereof as Kinase Inhibitors in Particular Ikk2 Inhibitors

Indole carboxamide compounds of Formula (I): are provided as inhibitors of kinase activity, in particular IKK2 activity as well as compositions and medicaments containing them, for use in inflammatory and tissue repair disorders.

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Bibliographische Detailangaben
Hauptverfasser: LONGSTAFF TIMOTHY, BAMBOROUGH PAUL, K KERNS JEFFREY, CHRISTOPHER JOHN ANDREW, MILLER DAVID DRYSDALE, BALDWIN IAN ROBERT
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Indole carboxamide compounds of Formula (I): are provided as inhibitors of kinase activity, in particular IKK2 activity as well as compositions and medicaments containing them, for use in inflammatory and tissue repair disorders.