INHIBITORS OF PHOSPHODIESTERASES IN INFERTILITY

The present invention is directed to methods of increasing oocyte production in a mammal. More specifically, the specification describes methods and compositions for inducing follicular maturation using a PDE inhibitor. The inhibitor may be used alone at high doses. Alternatively, the follicular mat...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: PALMER STEPHEN S, MACNAMEE MICHAEL C, ARKINSTALL STEPHEN J, ESHKOL ALIZA, MCKENNA SEAN D
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention is directed to methods of increasing oocyte production in a mammal. More specifically, the specification describes methods and compositions for inducing follicular maturation using a PDE inhibitor. The inhibitor may be used alone at high doses. Alternatively, the follicular maturation is achieved by combining a low dose of FSH with the PDE inhibitor treatment.