GEL FORMATION TO REDUCE HEMATOCRIT SENSITIVITY IN ELECTROCHEMICAL TEST

Devices for determining the concentration of a constituent in a physiological sample that comprise gel matrices to filter red blood cells are provided. Examples of such devices include a biosensor comprising, on a support substrate, a sample reception region for receiving a blood sample; at least on...

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Bibliographische Detailangaben
1. Verfasser:	BELL DOUGLAS E
Format:	Patent
Sprache:	eng
Schlagworte:	APPLYING LIQUIDS OR OTHER FLUENT MATERIALS TO SURFACES, IN GENERAL BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PERFORMING OPERATIONS PHYSICS PROCESSES FOR APPLYING LIQUIDS OR OTHER FLUENT MATERIALS TOSURFACES, IN GENERAL PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS SPRAYING OR ATOMISING IN GENERAL TESTING TRANSPORTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	Devices for determining the concentration of a constituent in a physiological sample that comprise gel matrices to filter red blood cells are provided. Examples of such devices include a biosensor comprising, on a support substrate, a sample reception region for receiving a blood sample; at least one electrode; and a reaction reagent system that is located in a gel matrix. The gel matrix disclosed herein is sufficient to prevent at least some of the red cells in the blood sample from contacting the electrode, and thus reduce the hematocrit sensitivity in the measurement.