2,6,8, Trisubstituted 1-deazapurines and their different uses

2,6,8, Trisubstituted 1-deazapurines and their different uses

The invention provides a compound having the structure of general formula (I): or a salt thereof, wherein, R represents hydrogen (except when R'=H), halogen, (substituted) alkyl except -CH3, (substituted) alkenyl, (substituted) alkynyl, or (substituted) -(CH2)n-aryl; R' represents hydrogen...

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Hauptverfasser: CHANG LISA CHUNG WAI, BRUSSEE JOHANNES, IJZERMAN ADRIAAN PIETER
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Sprache:eng
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CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator CHANG LISA CHUNG WAI
BRUSSEE JOHANNES
IJZERMAN ADRIAAN PIETER
description The invention provides a compound having the structure of general formula (I): or a salt thereof, wherein, R represents hydrogen (except when R'=H), halogen, (substituted) alkyl except -CH3, (substituted) alkenyl, (substituted) alkynyl, or (substituted) -(CH2)n-aryl; R' represents hydrogen (except when R=H), halogen, (substituted) alkyl except -CH3, (substituted) alkenyl, (substituted) alkynyl, or (substituted) -CH2)n-aryl; R'' represents hydrogen, -(CH2)n-hydroxyl, halogen, acyl, thio-acyl, seleno-acyl, (substituted) alkyl, (substituted) alkenyl, (substituted) alkynyl, or (substituted) -(CH2)n-aryl; and n is a number in the range from 0 to 10. The invention further provides pharmaceutical compositions comprising said compound, and the use of said compound to treat and/or prevent a variety of diseases.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title 2,6,8, Trisubstituted 1-deazapurines and their different uses
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