2,6,8, Trisubstituted 1-deazapurines and their different uses

2,6,8, Trisubstituted 1-deazapurines and their different uses

The invention provides a compound having the structure of general formula (I): or a salt thereof, wherein, R represents hydrogen (except when R'=H), halogen, (substituted) alkyl except -CH3, (substituted) alkenyl, (substituted) alkynyl, or (substituted) -(CH2)n-aryl; R' represents hydrogen...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: CHANG LISA CHUNG WAI, BRUSSEE JOHANNES, IJZERMAN ADRIAAN PIETER
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The invention provides a compound having the structure of general formula (I): or a salt thereof, wherein, R represents hydrogen (except when R'=H), halogen, (substituted) alkyl except -CH3, (substituted) alkenyl, (substituted) alkynyl, or (substituted) -(CH2)n-aryl; R' represents hydrogen (except when R=H), halogen, (substituted) alkyl except -CH3, (substituted) alkenyl, (substituted) alkynyl, or (substituted) -CH2)n-aryl; R'' represents hydrogen, -(CH2)n-hydroxyl, halogen, acyl, thio-acyl, seleno-acyl, (substituted) alkyl, (substituted) alkenyl, (substituted) alkynyl, or (substituted) -(CH2)n-aryl; and n is a number in the range from 0 to 10. The invention further provides pharmaceutical compositions comprising said compound, and the use of said compound to treat and/or prevent a variety of diseases.