Medical Device Including an Anesthetic and Method of Preparation Thereof

Non-metallic implantable medical devices including an anesthetic having a proton binding site with a non-ionic form and an ionic form. At least 5% w/w of the anesthetic is present with the proton binding site in the non-ionic form and the remainder of the anesthetic is present with the proton bindin...

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Hauptverfasser: ISCH ANDREW P, PEREZ-SEGARRA WALESKA, RUANE PATRICK H
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Non-metallic implantable medical devices including an anesthetic having a proton binding site with a non-ionic form and an ionic form. At least 5% w/w of the anesthetic is present with the proton binding site in the non-ionic form and the remainder of the anesthetic is present with the proton binding site in the ionic form. Methods of preparing such devices are also provided.