Vaccine Composition Against Rhodococcus Equi

The invention concerns a method for preparing a soluble antigenic extract from Rhodococcus equi, comprising a step of solubilizing membranes of said bacteria by contacting said bacteria with an extraction solution containing a nonionic detergent of sorbitan polyethylene fatty acid ester type. The in...

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Bibliographische Detailangaben
Hauptverfasser:	BALLET JEAN J, TAOUJI SAID, CAUCHARD JULIEN
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention concerns a method for preparing a soluble antigenic extract from Rhodococcus equi, comprising a step of solubilizing membranes of said bacteria by contacting said bacteria with an extraction solution containing a nonionic detergent of sorbitan polyethylene fatty acid ester type. The invention also concerns a soluble antigenic extract obtainable by said preparation method, said extract comprising membrane antigens of Rhodococcus equi dissolved in the extraction solution. Finally the invention concerns a composition comprising the soluble antigenic extract as medicine, comprising preferably a nanoparticulate or oil-in-water emulsion type adjuvant, and the use of the soluble antigenic extract for preparing a pharmaceutical composition for preventing or treating a Rhodococcus equi-induced infection in an animal.