Stable polymorphs of (E)-N,N-diethyl-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)acrylamide

Stable polymorphs of (E)-N,N-diethyl-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)acrylamide

The present invention provides stable crystalline polymorphic Form C and Form D of (E)-Entacapone, (E)-N,N-diethyl-2-cyano-3-(3,4-dihydroxy-5-henyl)acrylamide and processes for their preparation. The polymorphic Form C and Form D of (E)-Entacapone are characterized by specific Infra Red (IR) and X-r...

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Bibliographische Detailangaben
Hauptverfasser: KHAN RASHID ABDUL REHMAN, YADAV RAM PRASAD, SHAIKH ZAKIR GAFOOR, JAWEED MUKARRAM SIDDIQUI MOHAMMED
Format: Patent
Sprache:eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Zusammenfassung:The present invention provides stable crystalline polymorphic Form C and Form D of (E)-Entacapone, (E)-N,N-diethyl-2-cyano-3-(3,4-dihydroxy-5-henyl)acrylamide and processes for their preparation. The polymorphic Form C and Form D of (E)-Entacapone are characterized by specific Infra Red (IR) and X-ray powder diffraction peak values.