Selected CGRP-antagonists, process for preparing them and their use as pharmaceutical compositions

Selected CGRP-antagonists, process for preparing them and their use as pharmaceutical compositions

The present invention relates to the CGRP antagonists of general formula wherein A and R1 to R3 are defined as in claim 1 , the tautomers, the diastereomers, the enantiomers, the hydrates thereof, the mixtures thereof and the salts thereof and the hydrates of the salts, particularly the physiologica...

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Bibliographische Detailangaben
Hauptverfasser: SCHAENZLE GERHARD, DOODS HENRI, MUELLER STEPHAN G, ARNDT KIRSTEN, STENKAMP DIRK, RUDOLF KLAUS, LUSTENBERGER PHILIPP
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:The present invention relates to the CGRP antagonists of general formula wherein A and R1 to R3 are defined as in claim 1 , the tautomers, the diastereomers, the enantiomers, the hydrates thereof, the mixtures thereof and the salts thereof and the hydrates of the salts, particularly the physiologically acceptable salts thereof with inorganic or organic acids, pharmaceutical compositions containing these compounds, the use thereof and processes for the preparation thereof.