Stent For Placement In Body

It is intended to easily provide a stent for placement in body which can hold an increased amount of a drug without causing cracking or peeling in the coating layer with the dilation of the stent and from which the drug can be sustainedly released as far as possible. Namely, a stent for placement in...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: TAKIGUCHI YUKI, KAWATSU MASAJI, NAKANO RYOJI, NISHIDE TAKUJI, FUKAYA KOHEI
Format: Patent
Sprache:eng
Schlagworte:
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Beschreibung
Zusammenfassung:It is intended to easily provide a stent for placement in body which can hold an increased amount of a drug without causing cracking or peeling in the coating layer with the dilation of the stent and from which the drug can be sustainedly released as far as possible. Namely, a stent for placement in body having a coating layer mainly comprising a drug and a polymer in at least a part of the stent surface wherein the coating layer consists of an inner layer and an outer layer, the weight ratio of drug/polymer, which is defined based on the weights of the drug and the polymer contained in each layer, of the inner layer is higher than that of the outer layer, and the outer layer contains an efficacious amount of the drug.