Device and Method for Protein Analysis

A device for protein analysis or mapping, includes an array of particulate nanoparticles, wherein said nanoparticles are bound, preferably co-immobilized, at specific spots on a planar read-out surface or substrate and are provided with a plurality of capture probes for capturing proteins, preferabl...

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Bibliographische Detailangaben
Hauptverfasser: FROMELL KARIN, ANDERSSON MARGARETHA, DAHLGREN CALDWELL KARIN
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:A device for protein analysis or mapping, includes an array of particulate nanoparticles, wherein said nanoparticles are bound, preferably co-immobilized, at specific spots on a planar read-out surface or substrate and are provided with a plurality of capture probes for capturing proteins, preferably glycoproteins. A method in which the device is used for protein profiling, especially glycoprotein profiling, of individual samples with high sensitivity is also disclosed. The device and method do not require any complex sample preparation.