Rapidly disintegrating low friability tablets comprising silica materials

This invention pertains to the ability to provide rapidly disintegrating tablets through the inclusion of a silica material in combination with other common tablet components. Such a silica material must exhibit a sufficiently low surface area in order to boost the ability of the table to separate q...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: CORNELIUS JOHN M, MEHRA DEV K, WITHIAM MICHAEL C
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:This invention pertains to the ability to provide rapidly disintegrating tablets through the inclusion of a silica material in combination with other common tablet components. Such a silica material must exhibit a sufficiently low surface area in order to boost the ability of the table to separate quickly when introduced into a user's mouth cavity. Such a tablet is dimensionally stable prior to use (low friability) and, when immersed in water the tablet disintegrates therein in less than about 60 seconds.