FACTOR Xa INHIBITOR FORMULATION AND METHOD

An injectable Factor Xa inhibitor formulation is provided which includes the Factor Xa inhibitor razaxaban or apixaban, a solubilizing agent which is a substituted beta-cyclodextrin, preferably, sulfobutyl ether beta-cyclodextrin (SBE-CD) or hydroxypropyl-beta-cyclodextrin (HPB-CD), and water. A met...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	GOGATE UDAY S, MALLOY TIMOTHY M, NASSAR MUNIR N
Format:	Patent
Sprache:	eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	An injectable Factor Xa inhibitor formulation is provided which includes the Factor Xa inhibitor razaxaban or apixaban, a solubilizing agent which is a substituted beta-cyclodextrin, preferably, sulfobutyl ether beta-cyclodextrin (SBE-CD) or hydroxypropyl-beta-cyclodextrin (HPB-CD), and water. A method for preventing or treating venous thrombosis, deep venous thrombosis and acute coronary syndrome employing the above formulation is also provided.