Anti-angiogenic activity of 2-methoxyestradiol in combination with anti-cancer agents

The present invention relates generally to methods and compositions of treating disease characterized by abnormal cell proliferation and/or abnormal or undesirable angiogenesis by administering antiangiogenic agents in combination with chemotherapeutic agents. More specifically, the present inventio...

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Bibliographische Detailangaben
Hauptverfasser: STRAWN STEVEN J, PLUM STACY M, FOGLER WILLIAM E, TRESTON ANTHONY M, LAVALLEE THERESA M, SIDOR CAROLYN F
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates generally to methods and compositions of treating disease characterized by abnormal cell proliferation and/or abnormal or undesirable angiogenesis by administering antiangiogenic agents in combination with chemotherapeutic agents. More specifically, the present invention relates to a methods and compositions of treating diseases characterized by abnormal cell proliferation and/or abnormal or undesirable angiogenesis by administering 2-methoxyestradiol, in combination with chemotherapeutic agents.