System and method for imaging using distributed X-ray sources

A technique is provided for efficient dose management and/or scatter reduction during imaging. The technique includes estimating attenuation level of different portions of an imaged object, and independently adjusting at least one of X-ray flux and X-ray energy spectrum from each of a plurality of emission points of a distributed X-ray source based on the attenuation level of different portions of the imaged object. The technique also includes acquiring two or more projection images of different portions of an entire field of view via the distributed X-ray source, removing respective scatter components from each of the two or more projection images, and combining the projection images less scatter components to generate a final projection image of the entire field of view.