HMGCoA reductase inhibitor combinations and uses thereof

The invention provides a compound comprising a first pharmacological moiety connected to at least a second pharmacological moiety through a physiologically labile linker, or a salt thereof. The invention also provides a method of reducing cardiovascular disease or cardiovascular disease-related cond...

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Bibliographische Detailangaben
Hauptverfasser: CYNKOWSKA GRAZYNA, ASHTON PAUL, CYNKOWSKI TADEUSZ, SMITH THOMAS J
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention provides a compound comprising a first pharmacological moiety connected to at least a second pharmacological moiety through a physiologically labile linker, or a salt thereof. The invention also provides a method of reducing cardiovascular disease or cardiovascular disease-related conditions in an individual. The method involves administering to an individual with cardiovascular disease an effective amount of a compound, in which the compound has a first pharmacological moiety linked to a second pharmacological moiety, and the compound or either or both of the constituent pharmacological moieties acts to reduce, treat, or prevent cardiovascular disease. The compounds of the invention can be delivered in a drug delivery device.