Marburg I mutant of factor VII activating protease (FSAP) as risk factor for arterial thrombosis and methods of detecting FSAP and FSAP mutations

A novel arterial thrombosis risk factor comprising one or more of the identified mutants of coagulation factor VII-activating protease (FSAP) is described. In addition, diagnostic determination methods for detecting these mutants which are identified as risk factors are described.

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Bibliographische Detailangaben
Hauptverfasser: MUTH-NAUMANN GUDRUN, WIEDERMANN CHRISTIAN J, WEIMER THOMAS, KNOBLAUCH BERND, ROEMISCH JUERGEN, BECKER MARGRET, FEUSSNER ANNETTE, LANG WIEGAND, STOEHR HANS-ARNOLD, KIECHL STEFAN, WILLEIT JOHANN, NERLICH CLAUDIA, DOERSAM VOLKER
Format: Patent
Sprache:eng
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Zusammenfassung:A novel arterial thrombosis risk factor comprising one or more of the identified mutants of coagulation factor VII-activating protease (FSAP) is described. In addition, diagnostic determination methods for detecting these mutants which are identified as risk factors are described.