TAAR1 knock out animal

The present invention relates to a vector construct comprising genomic sequences homologous to upstream and downstream regions flanking the single coding exon of the TAAR1 gene, one or more selection marker genes and optionally a reporter gene and the use thereof. The present invention further provi...

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Bibliographische Detailangaben
Hauptverfasser: PAULY-EVERS MEIKE, HOENER MARIUS, LINDEMANN LOTHAR, MEYER AIKO C
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to a vector construct comprising genomic sequences homologous to upstream and downstream regions flanking the single coding exon of the TAAR1 gene, one or more selection marker genes and optionally a reporter gene and the use thereof. The present invention further provides TAAR1 knock-out animals and the use thereof.