Selected CGRP antagonists, processes for preparing them and their use as pharmaceutical compositions

The present invention relates to the CGRP-antagonists of general formula I wherein R1, R2, R3 and R4 are defined as in claim 1, the tautomers, the isomers, the diastereomers, the enantiomers, the hydrates thereof, the mixtures thereof and the salts thereof and the hydrates of the salts thereof, part...

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Hauptverfasser: PALEARI FABIO, SCHAENZLE GERHARD, DOODS HENRI, MUELLER STEPHAN G, ARNDT KIRSTEN, STENKAMP DIRK, RUDOLF KLAUS, LUSTENBERGER PHILIPP, SANTAGOSTINO MARCO
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention relates to the CGRP-antagonists of general formula I wherein R1, R2, R3 and R4 are defined as in claim 1, the tautomers, the isomers, the diastereomers, the enantiomers, the hydrates thereof, the mixtures thereof and the salts thereof and the hydrates of the salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids or bases, as well as those compounds of general formula I wherein one or more hydrogen atoms are replaced by deuterium, pharmaceutical compositions containing these compounds, their use and processes for preparing them.