Methods for preventing and treating metabolic disorders and new pyrazole-O-glycoside derivatives

The invention relates to methods for preventing or treating metabolic disorders, for improving glycemic control, for preventing progression from impaired glucose tolerance, insulin resistance and/or from metabolic syndrome to type 2 diabetes mellitus, for preventing or treating of complications of d...

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Hauptverfasser: PINNETTI SABINE, STREICHER RUEDIGER, HIMMELSBACH FRANK, DUGI KLAUS, FUJITA KOICHI, BARSOUMIAN EDWARD L, OHSUMI KOJI, ISHIDA NOZOMU, RITTER REGINE, MAEZONO KATSUMI, THOMAS LEO, MAIER ROLAND, EICKELMANN PETER, HATANAKA TOSHIHIRO
Format: Patent
Sprache:eng
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Zusammenfassung:The invention relates to methods for preventing or treating metabolic disorders, for improving glycemic control, for preventing progression from impaired glucose tolerance, insulin resistance and/or from metabolic syndrome to type 2 diabetes mellitus, for preventing or treating of complications of diabetes mellitus, for reducing the weight, for preventing or treating the degeneration of pancreatic beta cells, for treating hyperinsulinemia and insulin resistance and diabetes type 1, in patients in need thereof by administering a pharmaceutical composition comprising a pyrazole-O-glycoside as defined in claim 1, or a prodrug thereof, or a pharmaceutically acceptable salt thereof.