Dosage form comprising liquid formulation

A sustained release dosage form includes a capsule made of a thermoplastic polymer having a softening point below 200° C. and an orifice formed or formable within the capsule, an emulsion formulation contained within the capsule, and an expandable composition within the capsule remote from the orifi...

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Bibliographische Detailangaben
Hauptverfasser: WONG PATRICK S, DONG LIANGANG, ESPINAL STEVEN
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:A sustained release dosage form includes a capsule made of a thermoplastic polymer having a softening point below 200° C. and an orifice formed or formable within the capsule, an emulsion formulation contained within the capsule, and an expandable composition within the capsule remote from the orifice. The emulsion formulation comprises a drug, an emulsifying surfactant, and an oil. The expandable composition is configured to expand and expel the emulsion formulation through the orifice.