Method and Apparatus Including Use of Metalloporphyrins for Subsequent Optimization of Radiosurgery and Radiotherapy

An apparatus and method for subsequent optimization of radiosurgery and radiotherapy is provided. The invention includes administering a metalloporphyrin to the patient, and then creating a 3-dimensional mapping of tissue through use of PET or SPECT. Malignant and pre-malignant tissue has an affinit...

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1. Verfasser: ADAIR EDWIN L
Format: Patent
Sprache:eng
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Zusammenfassung:An apparatus and method for subsequent optimization of radiosurgery and radiotherapy is provided. The invention includes administering a metalloporphyrin to the patient, and then creating a 3-dimensional mapping of tissue through use of PET or SPECT. Malignant and pre-malignant tissue has an affinity for the metalloporphyrin. During treatment, real-time images are also provided which are compared to the previous 3-dimensional mapping. Creation of the real-time images is also achieved through PET or SPECT wherein a metalloporphyrin is administered to the patient. Total administration of radiation is calculated by summing radiation from the inetalloporphyrins and from the radiosurgery/radiotherapy. The amount of radiation delivered by the metalloporphyrins and by the radiosurgery/radiotherapy are adjustable based on a patient's response to the dual delivery.