3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands

There are disclosed compounds of the formula or a pharmaceutically acceptable salt or solvate thereof which are useful for the treatment of chemokine-mediated diseases such as acute and chronic inflammatory disorders and cancer.

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Bibliographische Detailangaben
Hauptverfasser:	LI GE, FERREIRA JOHAN A, LAI GAIFA, JAKWAY JAMES P, BIJU PURAKKATTLE J, CHAO JIANHUA, LUNDELL DANIEL, TAVERAS ARTHUR G, KAISER BERND, MERRITT J. R, YU YOUNONG, CHAO JIANPING, DWYER MICHAEL, HECKER EVAN A, ROKOSZ LAURA L, WU MINGLANG, NELSON KINGSLEY H.JR, BOND RICHARD W, AKI CYNTHIA J, FINE JAY S, BALDWIN JOHN J
Format:	Patent
Sprache:	eng
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	There are disclosed compounds of the formula or a pharmaceutically acceptable salt or solvate thereof which are useful for the treatment of chemokine-mediated diseases such as acute and chronic inflammatory disorders and cancer.