Phorboxazole compounds and methods of their preparation

Novel macrolactone compounds, their methods of preparation, pharmaceutical compositions containing these compounds, and methods for their pharmaceutical use are disclosed. In certain embodiments, the macrolactone compounds may be useful, inter alia, for treating various cancers, inducing apoptosis i...

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Hauptverfasser: ISHIKAWA TOMOYASU, RAZLER THOMAS M, SMITH AMOS B.III, HIROSE TOMOYASU, CIAVARRI JEFFREY P
Format: Patent
Sprache:eng
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Zusammenfassung:Novel macrolactone compounds, their methods of preparation, pharmaceutical compositions containing these compounds, and methods for their pharmaceutical use are disclosed. In certain embodiments, the macrolactone compounds may be useful, inter alia, for treating various cancers, inducing apoptosis in malignant cells, or inhibiting cancer cell division.