Benzimidazole derivatives as raf kinase inhibitors

The present invention relates to benzimidazole derivatives of formula I, the use of the compounds of formula I as inhibitors of one or more kinases, the use of the compounds of formula I for the manufacture of a pharmaceutical composition and a method of treatment, comprising administering said phar...

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Bibliographische Detailangaben
Hauptverfasser: BURGDORF LARS T, SIRRENBERG CHIRSTIAN, WIESNER MATTHIAS, ZENKE FRANK, BUCHSTALLER HANS-PETER, FINSINGER DIRK, AMENDT CHRIATIANE, GRELL MATTHIAS
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention relates to benzimidazole derivatives of formula I, the use of the compounds of formula I as inhibitors of one or more kinases, the use of the compounds of formula I for the manufacture of a pharmaceutical composition and a method of treatment, comprising administering said pharmaceutical composition to a patient. Accordingly, the compound of Formula I or a pharmaceutically acceptable salt thereof is administered for the treatment of diseases mediated by one or more kinase pathways, preferably by the raf kinase pathway, especially cancers, [FORMULA]