Vitamin d receptor modulators

The present invention relates to novel, non-secosteroidal, sulfonate and sulfonamide functional diaryl compounds with vitamin D receptor (VDR) modulating activity that are less hypercalcemic than 1alpha,25 dihydroxy vitamin D3. These compounds are useful for treating bone disease and psoriasis.

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	MA TIANWEI, JONES CHARLES D, NAGPAL SUNIL, GAJEWSKI ROBERT P, LU JIANLIANG, YEE YING K, LINEBARGER JARED H
Format:	Patent
Sprache:	eng
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The present invention relates to novel, non-secosteroidal, sulfonate and sulfonamide functional diaryl compounds with vitamin D receptor (VDR) modulating activity that are less hypercalcemic than 1alpha,25 dihydroxy vitamin D3. These compounds are useful for treating bone disease and psoriasis.