Immunoliposome composition for targeting to a HER2 cell receptor

Immunoliposome composition for targeting to a HER2 cell receptor

An immunoliposome composition comprised of liposomes bearing a ligand for targeting to cells expressing a growth factor receptor, such as HER2, is described. Binding of the immunoliposome to HER2-expressing cells results in internalization of the immunoliposome for cytoplasmic delivery of an entrapp...

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Hauptverfasser: KELLEY LAURA, GUO LUKE, WONG FRANCES M, HJORTSVANG KRISTEN, NAJAFI AZAR, ABRA ROBERT, HUANG ANTHONY
Format: Patent
Sprache:eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Zusammenfassung:An immunoliposome composition comprised of liposomes bearing a ligand for targeting to cells expressing a growth factor receptor, such as HER2, is described. Binding of the immunoliposome to HER2-expressing cells results in internalization of the immunoliposome for cytoplasmic delivery of an entrapped drug.