Fused heterocyclic derivates as ppar modulators

The present invention is directed to a method of treatment by modulating a peroxisome proliferator activated receptor by employing a compound of Structural Formula (I). The variables in I are defined herein. Also included are compounds, methods of making compounds, and pharmaceutical compositions. T...

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Bibliographische Detailangaben
Hauptverfasser: MAYHUGH DANIEL R, ZHU GUOXIN, SCHKERYANTZ JEFFREY M, CONNER SCOTT E, MANTLO NATHAN B, WANG XIAODONG, KNOBELSDORG JAMES A
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention is directed to a method of treatment by modulating a peroxisome proliferator activated receptor by employing a compound of Structural Formula (I). The variables in I are defined herein. Also included are compounds, methods of making compounds, and pharmaceutical compositions. The compounds of the present invention are believed to be effective in treating and preventing Syndrome X, Type H diabetes, hyperglycemia, hyperlipidemia, obesity, coagaulopathy, hypertension, atherosclerosis, and other disorders related to Syndrome X and cardiovascular diseases.