Protein kinase modulators and methods of use

Substituted aryl 1,4-pyrazine derivatives and their use in treating anxiety disorders, depression and stress related disorders are disclosed.

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Hauptverfasser: TESFAI ZEROM, CO ERICK W, MANN LARRY W, PETO CSABAJ, MANN GRACE, FORSYTH TIMOTHY P, BUHR CHRIS A, TSANG TSZE H, BAIK TAE-GON, RICE KENNETH D, EPSHTEYN SERGEY, CHEN BAILI, WANG LONGCHENG, KENNEDY ABIGAIL R, NUSS JOHN M, TAKEUCHI CRAIG S, ANAND NEEL K, DALRYMPLE LISA E, SHI XIAN, LEAHY JAMES W, CHEN JEFF, HUYNH TAI P, IBRAHIM MOHAMED A, MA SUNGHOON, DUBENKO LARISA
Format: Patent
Sprache:eng
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Zusammenfassung:Substituted aryl 1,4-pyrazine derivatives and their use in treating anxiety disorders, depression and stress related disorders are disclosed.