Process for the produciton of tibolone

Disclosed is a process for the synthesis of 17beta-hydroxy-7alpha-methyl-19-nor-17alpha-pregn-5(10)-ene-20-yne-3-one (ti-bolone, 11) and intermediates useful for the synthesis thereof: (11).

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Bibliographische Detailangaben
Hauptverfasser: MCHATTIE DEREK, GREENWOOD ALAN K, BHATARAH PARVEEN
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Disclosed is a process for the synthesis of 17beta-hydroxy-7alpha-methyl-19-nor-17alpha-pregn-5(10)-ene-20-yne-3-one (ti-bolone, 11) and intermediates useful for the synthesis thereof: (11).