Compositions and methods for treating heart failure

Certain substituted benzamide derivatives selectively modulate the cardiac sarcomere, for example by potentiating cardiac myosin, and are useful in the treatment of systolic heart failure including congestive heart failure.

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Bibliographische Detailangaben
Hauptverfasser: ELIAS KATHLEEN A, MALIK FADY, KRAYNACK ERICA A, FENG BAINIAN, TOMASI ADAM L, QIAN XIANGPING, LU PU-PING, MORGANS DAVID J.JR, SMITH WHITNEY W
Format: Patent
Sprache:eng
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Zusammenfassung:Certain substituted benzamide derivatives selectively modulate the cardiac sarcomere, for example by potentiating cardiac myosin, and are useful in the treatment of systolic heart failure including congestive heart failure.