Composition and method for covalently coupling an antithrombotic substance and a hydrophilic polymer

An antithrombotic composition includes a hydrophilic polymer backbone and an antithrombotic moiety covalently linked to the hydrophilic polymer backbone. The antithrombotic composition is formed by exposing a hydrophilic polymer including a hydroxyl group to an antithrombotic polysaccharide without...

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1. Verfasser:	ALEGRIA LARRY A
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES DISINFECTION, STERILISATION, OR DEODORISATION OF AIR HUMAN NECESSITIES HYGIENE MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES MEDICAL OR VETERINARY SCIENCE METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Zusammenfassung:	An antithrombotic composition includes a hydrophilic polymer backbone and an antithrombotic moiety covalently linked to the hydrophilic polymer backbone. The antithrombotic composition is formed by exposing a hydrophilic polymer including a hydroxyl group to an antithrombotic polysaccharide without having to first aminate the hydrophilic polymer.