Venlafaxine compositions comprising pellets with double layer coating

This invention provides coated pellets comprising a) a pellet core which comprises venlafaxine hydrochloride; b) a first coating which comprises a lipophilic layer or a sparingly water-soluble layer, and c) a second coating which comprises a water-insoluble polymer or polymer mixture. In another asp...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: SUKTHANKAR MANGESH, KULKARNI SUSHRUT, GOPINATHAN DINESH, THAKKER PRASHANT, DOSHI CHETAN C
Format: Patent
Sprache:eng
Schlagworte:
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Beschreibung
Zusammenfassung:This invention provides coated pellets comprising a) a pellet core which comprises venlafaxine hydrochloride; b) a first coating which comprises a lipophilic layer or a sparingly water-soluble layer, and c) a second coating which comprises a water-insoluble polymer or polymer mixture. In another aspect this invention provides compositions which comprises the coated pellets. In a further aspect, the invention provides a process for preparing the coated pellets which process avoids use of organic solvents at least for the second coating.