Method for determining the regulation of xenobiotic removal

The present invention relates generally to a method for identifying ligands that affect xenobiotic removal based upon their ability to modify the stability of receptors that regulate cytochrome P450 expression and/or drug transport proteins.

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Bibliographische Detailangaben
Hauptverfasser: RENTZEPERIS DIONISIOS, BONE ROGER F
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates generally to a method for identifying ligands that affect xenobiotic removal based upon their ability to modify the stability of receptors that regulate cytochrome P450 expression and/or drug transport proteins.