Novel proteins and nucleic acids encoding same

The present invention provides novel isolated polynucleotides and small molecule target polypeptides encoded by the polynucleotides. Antibodies that immunospecifically bind to a novel small molecule target polypeptide or any derivative, variant, mutant or fragment of that polypeptide, polynucleotide...

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Bibliographische Detailangaben
Hauptverfasser:	JI WEIZHEN, MALYANKAR URIEL, EDINGER SHLOMIT, GUNTHER ERIK, LOW KENNETH, GROSSE WILLIAM, LI LI, SHENOY SURESH, KEKUDA RAMESH, ZHONG MEI, QIAN XIAOZHONG, ZHONG HAIHONG, RASTELLI LUCA, MEZICK AMANDA, HERRMANN JOHN, ALSOBROOK JOHN, SMITHSON GLENNDA, ANDERSON DAVID, DHANABAL MOHANRAJ, VERNET CORINE, ETTENBERG SETH, LAROCHELLE WILLIAM, GERLACH VALERIE, GUO XIAOJIA, PATTURAJAN MEERA, MACLACHLAN TIMOTHY, WOLENC ADAM R, BERGHS CONSTANCE, SPYTEK KIMBERLY, STONE DAVID, BURGESS CATHERINE, MILLET ISABELLE, MCQUEENEY KELLY, GORMAN LINDA, GANGOLLI ESHA, MACDOUGALL JOHN, CASMAN STACIE, ELLERMAN KAREN, GUSEV VLADIMIR, BAUMGARTNER JASON, SUKUMARAN SUJATHA, MILLER CHARLES, SZEKERES EDWARD S.JR, PEYMAN JOHN, ROTHENBERG MARK, KHRAMTSOV NIKOLAI, PADIGARU MURALIDHARA, CATTERTON ELINA, RIEGER DANIEL, VOSS EDWARD, SHIMKETS RICHARD, BOLDOG FERENC, LIANG HONGPING
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA DERIVATIVES THEREOF ENZYMOLOGY MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS SUGARS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention provides novel isolated polynucleotides and small molecule target polypeptides encoded by the polynucleotides. Antibodies that immunospecifically bind to a novel small molecule target polypeptide or any derivative, variant, mutant or fragment of that polypeptide, polynucleotide or antibody are disclosed, as are methods in which the small molecule target polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states. More specifically, the present invention discloses methods of using recombinantly expressed and/or endogenously expressed proteins in various screening procedures for the purpose of identifying therapeutic antibodies and therapeutic small molecules associated with diseases. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.